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ID: PS-193

PhD Biological Sciences

7+ years experience
USA

About

This expert is a research professional and also a published author, with a total of 53 publications, among which 13 are in SCI indexed journals. Also, he is a reviewer for a number of peer-reviewed journals.

Areas of expertise

Cell and Molecular Biology, Cellular Mechanobiology, Microfluidics

Education

National University of Singapore, Mechanobiology Institute, Singapore

PhD in Biological Sciences (Mechanobiology), 2014 4.32/5

SASTRA University, Thanjavur, India

B.Tech. in Bioengineering, 2009

Certificates and awards

Academics

Awarded as Best Outgoing Student of the Department of Bioengineering, SASTRA University, India in 2008-09

Listed in Dean’s List for academic excellence in 2nd year and 3rd year (2007 and 2008) and Merit List in 1st year (2006)

Awarded for academic excellence consistently in 1st and 2nd year (2006 and 2007)
Co-curricular Academics

3rd Prize for Contraptions in PRAGYAN 2008 at National Institute of Technology, Tiruchchhirapalli, India

Work experience

Institut Jacques Monod, Université Paris Diderot/CNRS, Paris, France
Research Fellow with Prof. Benoit Ladoux and Prof. René-Marc Mège June 2016 – Present
In vitro reconstitution of cell-cell adhesion machinery

Purification of α-Catenin and Talin and reconstruction of the interaction of cell-cell adhesion proteins and actomyosin network using micropatterning and microfabrication.

Studied protein interaction dynamics by TIRF and epifluorescence microscopy.

Developed methods to measure forces by micropillars during unfolding of α-Catenin by actomyosin bundles.


Department of Biomedical Engineering, National University of Singapore, Singapore
Research Fellow with Prof. Lim Chwee Teck April 2015 – May 2016
Collective cell migration in microtubes

Studied tube formation of epithelial (Madin-Darby Canine Kidney; MDCK) and endothelial (EAHY 962) cells in 50-250µm tubes.

Performed image analysis and particle image velocimetry (PIV) to measure cell tube migration dynamics.

Developed a microfluidic platform to imitate blood flow in the presence of endothelial cell tubes of variable sizes.

Trained new students and undergraduates in cell culture and general laboratory practices.


Mechanobiology Institute, National University of Singapore, Singapore
Safety lead with Prof. Lim Chwee Teck November 2014 – May 2016

Ensured safety and organisation in Prof Lim Chwee Teck’s group in Mechanobiology Institute.

Compiled Risk Assessments and Standard Operating Procedures for the group.

Managed consumables and equipment for the group.


Mechanobiology Institute, National University of Singapore, Singapore
Research Assistant with Prof. Lim Chwee Teck November 2014 – March 2015
Human Mesenchymal Stem Cell differentiation on highly wrinkled carbon substrates

Evaluated the difference in proliferation and lineage determination process of human Mesenchymal Stem Cells on 6 carbon substrate with varied roughness and wrinkling.

Adopted immunocytological techniques and confocal microscopy to quantify the differentiation phenomenon.

Trained new students, research assistants and undergraduates in Microfabrication.


Mechanobiology Institute, National University of Singapore, Singapore
Graduate Student with Prof. Lim Chwee Teck and Prof. Michael Sheetz August 2009 – December 2014

Effects of fluid shear stress on Mesenchymal Stem Cell contractility and fate

Developed a microfluidic system to apply fluid shear stress on sin

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