{"id":7927,"date":"2017-06-09T18:00:35","date_gmt":"2017-06-09T12:30:35","guid":{"rendered":"https:\/\/www.enago.com\/academy\/?p=7927"},"modified":"2023-11-17T18:54:32","modified_gmt":"2023-11-17T12:54:32","slug":"karl-deisseroth-takes-2017-else-kroner-fresenius-prize","status":"publish","type":"post","link":"https:\/\/www.enago.com\/academy\/karl-deisseroth-takes-2017-else-kroner-fresenius-prize\/","title":{"rendered":"Karl Deisseroth Takes the 2017 Else Kr\u00f6ner Fresenius Prize"},"content":{"rendered":"

\nImage credits: Natalia Kepesz via ekfs.de<\/a><\/em><\/h6>\n

Prof. Karl Deisseroth, of Howard Hughes Medical Institute and Stanford University, is the recent winner of the Else Kr\u00f6ner Fresenius Prize. This Prize is given once every four years and has a total value of \u20ac4 million. Prof. Deisseroth has won many other science awards<\/a>, including the Massry Prize, the Dickson Prize in Medicine, and the Keio Medical Science Prize. The Fresenius Research Prize was given specifically for his contributions<\/a> to optogenetics, CLARITY, and his research in the neural circuit basis of depression.<\/p>\n

Dr. Karl Deisseroth is based at Stanford and is a neuroscientist and practicing psychiatrist involved in psychiatric disorders research. The Stanford psychiatrist pioneered optogenetics, in which light is used to precisely control neuronal activity in animals which can move freely. It involves inserting genes for light-sensitive proteins into neurons. This allows researchers to control the cells\u2019 signaling activity with a pulse of laser light. Turning cell signals on and off allows scientists to determine the role played by a set of neurons in the brain.<\/p>\n

The award given to Prof. Deisseroth was also for his work in hydrogel-tissue chemistry. His lab developed CLARITY, a hydrogel method that makes intact tissue samples or even whole organs of small animals transparent. The tissue\u2019s fatty substances make it opaque. CLARITY involves replacing the fatty tissue with a hydrogel that allows light transmission and enables large molecule transit (such as labeled antibodies or oligonucleotides) which can help to identify if certain proteins or DNA sequences are present in the tissue.<\/p>\n

He\u00a0also has an interest in psychiatric disorders. His active psychiatric practice has motivated him to understand the basis of these disorders. CLARITY and optogenetics are methods that he and his team have used to understand psychiatric disorders and also to\u00a0identify the neural circuits involved in various aspects of depression including anhedonia and hopelessness.<\/p>\n

The Else Kr\u00f6ner Fresenius Prize is given once every four years by the Else Kr\u00f6ner Fresenius Foundation. The foundation also promotes the training of medical personnel active in dialysis, health care, or nursing. Prof. Karl Deisseroth\u2019s award will be split between research (\u20ac3.5 million) and his personal use (\u20ac500,000). The Else Kr\u00f6ner Fresenius Prize is a fitting way to honor Prof. Deisseroth\u2019s many scientific achievements.<\/p>\n

 <\/p>\n

\n\t\t<\/a>\n\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Image credits: Natalia Kepesz via ekfs.de Prof. Karl Deisseroth, of Howard Hughes Medical Institute and…<\/p>\n","protected":false},"author":6,"featured_media":7931,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"footnotes":""},"categories":[757,758],"tags":[1527],"ppma_author":[1894],"class_list":["post-7927","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news","category-publishing-hot-topics","tag-highly-cited-researchers"],"better_featured_image":{"id":7931,"alt_text":"Else Kr\u00f6ner Fresenius Prize","caption":"Image by Natalia Kepesz sourced via ekfs.de","description":"Image by Natalia Kepesz sourced via ekfs.de","media_type":"image","media_details":{"width":930,"height":300,"hwstring_small":"height='41' 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